Desvenlafaxine is used to treat which of the following conditions?

• A. Major depression
• B. Bipolar I disorder
• C. Schizophrenia
• D. Obsessive-compulsive disorder

Answer: (A)

Desvenlafaxine is an antidepressant in the serotonin-norepinephrine reuptake inhibitor (SNRI) class used primarily to treat major depressive disorder. By blocking the reuptake of serotonin and norepinephrine, it increases their levels in the brain, which can help alleviate depressive symptoms such as low mood, loss of interest, fatigue, and sleep disturbances. This mechanism aligns with its approved use for major depressive disorder, making it the best answer.

The other conditions listed are not approved indications for desvenlafaxine. Bipolar I disorder often requires mood stabilizers and sometimes antipsychotics to manage mood swings and prevent mania. Schizophrenia is treated mainly with antipsychotic medications and psychosocial care. Obsessive-compulsive disorder is typically addressed with high-dose selective serotonin reuptake inhibitors (often different agents) or clomipramine, rather than desvenlafaxine.