Lithium therapy can cause which unusual taste sensation?

• A. Rash
• B. Nausea
• C. Metallic taste
• D. Insomnia

Answer: (C)

Lithium can cause a metallic taste, a form of dysgeusia. This unusual taste alteration is a recognized side effect of lithium therapy. The exact mechanism isn’t fully understood, but it’s thought to involve how lithium affects taste bud signaling or the electrolyte balance in saliva, subtly changing gustatory perception. It often appears when starting treatment or with higher levels. If this occurs, clinicians check the lithium level and hydration status, and consider dose adjustments if needed. Other listed effects like rash, nausea, or insomnia can occur with lithium, but they are not taste changes.