Which food should be avoided with phenelzine due to tyramine content?

• A. Rice
• B. Red wine
• C. Bananas
• D. Apples

Answer: (B)

When taking phenelzine, a monoamine oxidase inhibitor, foods high in tyramine must be avoided because tyramine isn’t broken down efficiently and can trigger a surge of norepinephrine, leading to a dangerous rise in blood pressure (hypertensive crisis). Red wine is a well-known tyramine-rich beverage, especially when aged, making it risky to consume with MAO inhibitors. In contrast, rice, bananas, and apples have low tyramine levels, so they’re generally safer choices with this medication. Always follow your clinician’s specific dietary guidance around tyramine-rich foods.