Which of the following is an MAOI?

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Study for the Galen Pharmacology Exam 1 Test. Use flashcards and multiple choice questions with hints and explanations. Achieve exam success!

Multiple Choice

Which of the following is an MAOI?

Explanation:
Monoamine oxidase inhibitors block the enzyme that breaks down monoamines in the brain, raising levels of serotonin, norepinephrine, and dopamine to improve mood. Phenelzine is a classic MAOI, irreversibly inhibiting MAO-A and MAO-B. The other drugs belong to different classes—desvenlafaxine is an SNRI, amitriptyline is a TCA, and lithium is a mood stabilizer—so they do not inhibit monoamine oxidase. Therefore, Phenelzine is the MAOI.

Monoamine oxidase inhibitors block the enzyme that breaks down monoamines in the brain, raising levels of serotonin, norepinephrine, and dopamine to improve mood. Phenelzine is a classic MAOI, irreversibly inhibiting MAO-A and MAO-B. The other drugs belong to different classes—desvenlafaxine is an SNRI, amitriptyline is a TCA, and lithium is a mood stabilizer—so they do not inhibit monoamine oxidase. Therefore, Phenelzine is the MAOI.

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